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Jastreboff et al., 2022) documented superior weight loss and glycemic control compared to single-target GLP-1 agonists, with up to 22.5% body weight reduction at 72 weeks in the SURMOUNT-1 trial

10.1016/j.sleep.2020.10.018 34 YamatsuA.YamashitaY.MaruI.YangJ.TatsuzakIJ.KimM

Ten paradoks jest typowy dla caej klasy peptydw regeneracyjnych: silny sygna z modeli zwierzcych, brak domknicia badaniami klinicznymi III fazy u ludzi

Reframing this as successful adaptation rather than declining effectiveness helps maintain perspective

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