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BACH1 influences the cellular response to oxidative stress by balancing oxidants and antioxidants

In both cases, modifications made to the structures of the peptides cause their bioavailability to be increased dramatically compared to the hormones secreted naturally by the intestine, from just a few minutes to more than a hundred hours, which allows these drugs to be administered by subcutaneous injection only once a week

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For example, in muscle, IRS-1 is more related to glucose uptake whereas IRS-2 stimulates the MAPK pathway [121]

They also conclude that this transporter may be used in insulin resistance treatment