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This is where most damage occurs

Microglia/macrophages are activated into M1 type and secrete pro-inflammatory cytokines such as IL-1, TNF-, and reactive oxygen species (ROS) (Eva and Roland, 2014

Standard dosing may be unsafe in these patients, necessitating individualized dose adjustments based on creatinine clearance or liver function tests

All volunteers had to abstain from other medications, supplementary vitamins, and alcohol intake for 2 weeks prior to enrollment and throughout the study

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Complete our online health assessment, share relevant medical history (particularly asthma, liver, or kidney issues), and connect with a licensed provider