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It upregulates vascular endothelial growth factor (VEGF) and its receptor VEGFR2, directly promoting angiogenesis the formation of new blood vessels at injury sites

3.3.5 Microbiome and metabolite therapy Its tangential but notable that the gut microbiome can release metabolites (like short-chain fatty acids) that influence host mitochondria and immunity

miR-335 increases iron release, lipid peroxidation, and ROS accumulation by degrading FTH1, and reduces mitochondrial membrane potential (MMP), thereby promoting ferroptosis [131] (Table 1)

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Synthesis of ROS-sensitive polymers conjugated with Ru(II)-OH (P4) At room temperature, 4-Dimethylaminopyridine (DMAP, 126 mg) was introduced to a solution of Ru(II)-OH (50 mg) and 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride (EDCl, 200 mg)