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Additionally, the current study showed that in rats with GN-induced ARF, our treatment regimens, which include solo LS, GSH, and their combination in both NP formulations, significantly reduced serum cystatin C levels and renal tissue concentrations of NGAL and KIM-1, indicating a linked improvement in ARF

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This method is more realistic than rigid docking and has proven effective, particularly in HIV drug discovery efforts since the early 2000s

An overflow of glutamate (the main endogenous excitatory amino in brain, at concentration of 515 mmol glutamate per kg body weight, higher than of any other neurotransmitter) is implicated in major psychiatric illnesses [1, 24,25,26]

However, unlike GPx4, GPx7 does not contain a glutathione binding site (Pei et al

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