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The peptide specifically upregulates genes for both type I collagen, which provides structural strength, and type III collagen, which contributes to tissue flexibility and elasticity

10.1038/s41598-018-26704-x [DOI] [PMC free article] [PubMed] [Google Scholar] Koike H., Ishida A., Hayashi T., Shimamura M., Mizuno S., Nakamura T., et al

Data collected during the probe trials time spent in the target quadrant and entries into the target quadrant) were also analyzed using one-way One-way ANOVA was used to analyze the dendritic spine results and significant effects were analyzed by Tukey post-hoc test

In adults, treatment length varies based on symptom relief and IGF-1 targets, and some may use it indefinitely if benefits persist (with periodic re-evaluation)

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D., Olivera, C., Olmedo, G., Omuto, C., Ortiz, S., Pascale, C., Pfeiffer, M., Ramos, I