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Sometimes, its as simple as diet

Selenium depletion affects the biosynthesis of GPX4 and subsequent antioxidative activity [48]

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Plant Species Biol 30(3):231236 Zhang X, Zou Z, Zhang J, Zhang Y, Han Q, Hu T, Xu X, Liu H, Li H, Ye Z (2011) Over-expression of sly-miR156a in tomato results in multiple vegetative and reproductive trait alterations and partial phenocopy of the sft mutant