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1,325 CKD can progress to end-stage renal disease (ESRD), which requires dialysis or kidney transplantation and increases the risk of CVD

10.3390/ijms232214024 327 ZhouQ.ZhangW.-X.HeZ.-Q.WuB.-S.ShenZ.-F.ShangH.-T.et al (2020)

As well as being a precursor to several diseases, oxidative stress is also believed to cause inflammation and contribute to visible aging

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Alternatively, uniformly 13 C-labelled (U- 13 C) yeast extracts offer a rich source of isotopically labelled metabolites derived from evolutionarily conserved primary metabolomes