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Compared with conventional 2D cell cultures, 3D organoids or spheroids, either scaffold-based or scaffold-free, better recapitulate the in vivo microenvironment, enhance biological relevance, and enable mechanistic investigations of drug responses in a tissue-mimetic context

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[DOI] [PMC free article] [PubMed] [Google Scholar] 183.Trivedi H., Daram S., Szabo A., Bartorelli A.L., Marenzi G

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