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(2009) Focus on mammalian thioredoxin reductases important selenoproteins with versatile functions, Biochim

As previously stated, inflammation is most often caused by a past injury, however, inflammation can also be an allergic reaction to constant intake of environmental toxins such as pesticides, heavy metals and bacterial exposure

In hypoxic disc environments, hypoxia-inducible factor 1 alpha (HIF-1) activates autophagy pathways, helping to mitigate ROS generation while promoting chondrogenic differentiation and cartilage matrix synthesis [84]