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For example, inhibition of respiration leads to a transcriptional switch in the expression of TCA cycle genes in fission yeast to replenish TCA cycle metabolites that support anabolic pathways (Liu and Butow, 1999)

Despite the fact that peptide ligands are relatively flexible and have a lower binding affinity to receptors compared with antibodies, the use of peptides in theranostic nanomedicine offers advantages because they are smaller, have reduced immunogenicity, have high multivalency, penetrate deep into tumors, are simpler to synthesize, and are cost-effective in production

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The present invention provides copper peptide reservoir in gel form wherein gelling agent selected makes sustained release of copper peptide over considerable long time such that the patch shall not be changed over 12 hrs, preferably over 24 hrs and most preferably over 48 hrs