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In their review, Du, Cullen and Buettner described that the concentration of dianionic ascorbate increases by a factor of 10 for every pH unit increase (Du et al., Clinical perspective Given the effect of vitamin C on normal physiology, it is apparent that it plays a role in the maintenance of homeostasis

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Uruno A, Yagishita Y, Katsuoka F, Kitajima Y, Nunomiya A, Nagatomi R, et al

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Further understanding of the importance of ROS in normal physiological processes and rationally designed antioxidants that do not undermine normal physiology, but might be effective under pathological conditions, are both needed

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On the other hand, it is also related to the drug resistance and radiation resistance of lung cancer, and has great significance in the research of ferroptosis in lung cancer

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The non-canonical NF-B pathway and its contribution to -cell failure in diabetes

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Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5% of body weight

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