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"Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes"

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Bourgis F., Roje S., Nuccio M.L., et al

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Meanwhile, calcium (e.g., CCAMK, CML31 , and CPK2 ), phytohormones (e.g., IAA30, GA2OX8, PYL8, ARR9 , and ERF061 / 118 ), and MAPK signaling pathway (e.g., MPK9 / 19/20, NPK1, MEKK1 , and YDA ), transcription regulation (e.g., C3H, NAC002, MYB108, WRKY71, BHLH35 , and VIP1 ) and ubiquitin-26S proteasome system (e.g., XERICO and KEG ) were further activated by combined CD stress

Clinical implications of gut modulation in AF include personalized dietary strategies, microbiome assessment through metagenomic sequencing, and targeted interventions such as SCFA-based therapies and ferroptosis inhibition