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However, disposing of the need for adjuvant chemotherapy still requires further evidence and studies

This is particularly true in instances such as anogenital lichen planus and lichen sclerosus where extraordinarily long-lasting hyperpigmentation may first be noted a very long time after any clinical evidence of inflammation has resolved

Hodis E, Watson IR, Kryukov GV, Arold ST, Imielinski M, Theurillat JP, Nickerson E, Auclair D, Li L, Place C, Dicara D, Ramos AH, Lawrence MS, Cibulskis K, Sivachenko A, Voet D, Saksena G, Stransky N, Onofrio RC, Winckler W, Ardlie K, Wagle N, Wargo J, chong K, Morton DL, Stemk-Hale K, Chen G, Noble M, Meyrson M, Ladbury JE, Davies MA, Gershenwald JE, Wagner Sn, Hoon DSB, Shadendorf D, Lander ES, Gabriel SBl, Getz G, Garraway LA, Chin L

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Symptoms include a dark area on the vulva that may be raised, vulvar pain or soreness, itchiness, and urination pain

Benign naevi may result in one or more parallel longitudinal bands of pigment on the nail plate