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Several inhibitors of G6PD and IDH, such as RRx-001, DHEA and AG-881, have demonstrated promising efficacy and have entered Phase III clinical trials (55)

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Three Tn sugar antigens linked to glycosylation sites bind tetanus toxoid to produce a vaccine which, without support by an adjuvant, elicited the strongest immune response (endpoint titer 100 000) and antibodies binding to tumor cells