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We also discuss how these developments are providing important lessons for the emerging second generation of combinatorial ('SMN-plus') therapies that are likely to be required to generate robust treatments that are effective across a patient's lifespan

Astrocytes are key in maintaining the BBB, blood flow, and neuronal metabolism [82, 83]

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Treatment of Mecp2 mutant mice with IGF1 significantly increases spine density (with no mention of improvements in dendritic arbor

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