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Description

Sodium lactate versus mannitol in the treatment of intracranial hypertensive episodes in severe traumatic brain-injured patients

Fernstrom JD

doi: 10.1038/nm817

Discussion Here we show that -glutamylcysteine is a thiol-redox regulator that efficiently detoxifies mitochondrial ROS

NagelkerkeAVan KuijkSJMartensJWSweepFCHoogerbruggeNBussinkJet al

In vascular smooth muscle cells from large arteries, NOX1 is required for migration, hypertrophy, and proliferation, NOX4 mediates differentiation, and NOX1 and 2 are implicated in hypertension