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For obese patients (including sarcopenic obese), energy intake should not exceed the recommendations for healthy adults expressed in kcal/kg body weight, but should also focus on protein intake and physical exercise to preserve muscle mass and respiratory muscle function [38]

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Of these 31 patients, 26 patients had 1 immune-related adverse event, 4 patients had 2 immune-related adverse events, and 1 patient had 3 immune-related adverse events, for a total of 37 immune-related adverse events

Ubiquitination events happen in the heat/cold shock response