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Susceptibility to toxicity increases with higher amount of alcohol intake thus increasing the risk of liver injury

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Leaky Gut Syndrome, also known as Intestinal Permeability, occurs when the tight junctions in the gut lining become loose, allowing food particles and inflammatory lipopolysaccharides (LPS) to leak into the bloodstream

To achieve comparable effects, oral doses must be 30-50 times higher, creating cost and side effect challenges

B.Imam AliaganA

Nrf2 predominantly governs antioxidant defenses by neutralizing ROS, whereas FXR plays a key role in maintaining bile acid balance and mitigating bile acid-driven oxidative stress [147]