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The competition among oral GLP-1 small molecules benefits patients in several ways: price competition should lower treatment costs, different pharmacokinetic profiles provide options for patients who don't tolerate one agent, and the pressure to differentiate drives development of improved formulations

In particular, the pro-inflammatory state observed during the aging process may provide a link between cytokine-induced CD38 expression, age-related tissue NAD decline, and the inflammaging theory [1, 53]

Additionally, the familiar home environment can increase comfort with the process for some patients