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Compared to mTYR, the hTYR pocket contains more acidic amino acids, including Asp167, Asp178, Asp180, Asp286, and Glu184 (Table 1)

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doi: 10.20452/pamw.16656 98 PonticelliCMoroniG

Drug - Methotrexate, MTX Methotrexate Toxicity- Treatment - - Sulfasalazine, SSZ - Hydroxychloroquine, HCQ - Steroids - Anti-TNF Biologic Agents - (Humira, Adalimumab) C C-Reactive Protein- CRP - ESR Rheumatoid Factor (RF)