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A large cohort study of 3,236 participants over 21 years shows compelling observational links between plasma ET and reduced cardiovascular mortality, but causality is not established

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Cell Mol Immunol 23 , 743772 (2026)

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The Henderson-Hasselbalch equation allows us to determine the charge state of any ionizable group given its pKa

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Overall, this ROS-induced autophagy serves as a crucial response to oxidative stress, enabling cells to adapt to adverse conditions and enhance survival

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During the early stages of iron overload, a significant amount of released iron is transported to the mitochondria as a buffer, and mitophagy may segregate iron into the mitophagosomes and decrease the origin of ROS for ferroptosis [65, 66]

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