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Takahashi, C., Muramatsu, R., Fujimura, H., Mochizuki, H

To investigate this idea, we evaluated de novo and salvage pyrimidine synthesis pathways in a panel of cell lines by quantifying UMP labelling from amide- 15 N-glutamine and 15 N 2 -uridine tracers

(nmol/mg Hb)

Here, we see that 5FU can induce changes in mitochondrial abundance in HCT116 cancer cells but fails to induce similar changes in hMSCs, evidenced by NAO staining and protein expression (Extended Data Fig