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PMID: 65 JeongJHJungJHLeeJSOhJSKimY-GLeeC-Ket al

The copper(II) ion at the centre of each GHK-Cu molecule acts as a cross-linker between peptide chains when thermal energy or mechanical shear disrupts the coordination sphere, causing visible protein clusters that scatter light and produce the cloudy appearance

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10 L of isotonic saline containing 100 g/mL Nle-YI-(6) aminohexanoic amide as an internal standard is added to each sample on ice

For instance, DSF-induced inhibition of PI3K-Akt signaling leads to decreased NF-B activity, illustrating a broader antifibrotic effect (Kanai et al., 2010)