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Those with known allergy to B12 or cobalt should avoid

Once the rash appears, the bullseye rash in particular is a telltale sign of Lyme disease, even though some patients never get one

Indigestion or dyspepsia may present as a burning sensation, acid reflux, or general digestive discomfort, though there is no established link between B12 and gastro-oesophageal reflux disease

The injectable form is typically used when oral administration is not feasible or not sufficiently effective

Systolic and diastolic left ventricular function in children with primary hypertension: a systematic review and meta-analysis

You can still get B12 from dairy products, fortified cereals, and fortified non-dairy products if you're vegetarian