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10.1038/s41580-020-0230-3 140 SongA.ZhangS.ZhaoX.WuS.QiX.GaoS.et al (2023)

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Statins and vitamin K biology Several mechanistic and clinical papers suggest an interaction between statins and vitamin-Krelated pathways: Okuyama and colleagues proposed that statins inhibit vitamin K2 synthesis and selenoprotein production, contributing to arterial calcification and heart failure risk