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Correlating brain metrics (hippocampus volume and gFA in the fornix) with redox markers (GSH levels and GPx activity) generated four comparisons, and thus the alpha level to detect significant correlations was set to 0.01

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When GPX4 activity is hindered, lipid peroxides accumulate and ultimately cause cell death

This activation induces the transcription of antioxidant response element (ARE)-regulated genes, including heme oxygenase-1 (HO-1), SOD, catalase, and glutathione peroxidase