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Certain people who may not be getting enough Vitamin B12 or have trouble absorbing it are: People with pernicious anemia, an autoimmune disease, have trouble absorbing Vitamin B12 from foods and dietary supplements

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In conditions with low H 2 S signaling (such as heart failure with reduced ejection fraction), SQOR inhibition may be beneficial to restore H 2 S levels, whereas in conditions primarily involving mitochondrial dysfunction (such as ischemiareperfusion injury), SQOR activation may be advantageous to support mitochondrial function

PMCID: PMC7353203