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Aging Cell 23 , e14145 (2024)

PMID: 27801522 www.ncbi.nlm.nih.gov/pubmed/27801522

For instance, METH exposure has been shown to increase expression of the pro-apoptotic proteins Bax, Bad, and Bid ( Several studies have reported that multiple molecules are involved in the apoptotic death of neurons induced by METH

Several PD studies reported an extensive cortical hypometabolism of glucose, while only some of these investigations concomitantly show increased glucose metabolism in diverse subcortical regions (35, 52)

Lauric acid, the primary component of coconut oil, affects microglial activation through the G protein-coupled receptor (GPR40)-dependent pathway, reducing activation of glial cells and further neuronal damage in Alzheimer's disease

Therefore, GPx and Prx2 can have a direct role on RBC membrane antioxidant defense