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BMC Psychiatry 2022;22:34

It was that clinicians need to understand the current lack of evidence, and that indications, dosing, frequency, treatment duration, safety and efficacy remain unknown

For example, studies have demonstrated the occurrence of mitochondrial heterogeneity in dopaminergic neurons in the substantia nigra of patients with PD

PMID: 32 AcostaJCBanitoAWuestefeldTGeorgilisAJanichPMortonJPet al

The right option depends on eligibility, safety, and ongoing supervision, not a generic plan copied from another person

This enables precision tailoring of nanoparticle formulations to reduce inter-individual variability and improve safety-efficacy balance