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Excretable hydrophilic metabolites are usually produced during phase II metabolism by glutathione S-transferases, uridine 5-diphospho (UDP)-glucuronosyltransferases, sulfotransferases, N-acetyltransferases, and epoxide hydrolases

it is one of the most important antioxidant because its within the cell

Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis

Specifically, cannabinoids are substrates of the CYP enzyme family [165]

When the autophagy flux is compromised, Nrf2 signaling is activated

Therefore, identification of the molecular mechanisms leading to MASLD-related fat accumulation, mitochondrial dysfunction, and oxidative stress is necessary to facilitate the development of specific interventions aimed at preventing the progression of hepatic steatosis