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Vitamin B12 plays an important role in energy metabolism, red blood cell production, nerve function, and DNA synthesis

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Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)

To absorb vitamin B12 effectively, your body requires an intact stomach and gut, a well-functioning pancreas, and sufficiently high levels of intrinsic factor, a protein that binds to vitamin B12 in the stomach (1)

Low vitamin B12 can cause fatigue, weakness, memory problems, tingling in the hands and feet, and pale skin

Brand-name semaglutide costs $1,000 to $1,600, while compounded versions range from $150 to $500