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337 Additionally, navitoclax (also known as ABT-263) is a drug classified as a Bcl-2 family inhibitor. It specifically inhibits the antiapoptotic proteins Bcl-2, Bcl-xL, and Bcl-w within the Bcl family and induces apoptosis through the activation of caspase signaling pathways

While observational studies provide valuable hypotheses and biological plausibility, clinical recommendations should primarily be guided by interventional data, which are currently strongest for certain dietary patterns and weaker for isolated nutrient supplementation

Notably, SPRTN is unable to process crosslinks on strictly dsDNA or ssDNA substrates

Gubern et al

[Abstract] Proliferation ability of MDA-MB-231 and HS578T cells in control and Losartan (10M)-treated groups was assessed by colony formation assay