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Excess iron, due to its catalysis of one electron redox chemistry, plays a key role in the formation of toxic oxygen radicals

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The distinctive metabolism of cancer cells, their specific mutations with regard to certain tumor suppressors or oncogenes, the imbalances in terms of ferroptosis defenses, and high ROS loads render some tumor cells vulnerable to ferroptosis [6,7,8], which has been proven to be an effective method for cancer treatment