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The same dilution procedure was performed using water for injection as a control group

We further evaluated the selectivity of most active compounds ( 9r , 9m , 9d and 9h ) against HDAC1 as a representative of class I HDAC enzymes, HDAC4, a member of class IIa, HDAC6 and HDAC10 from class IIb and HDAC11, the only member of class IV

The pharmacodynamic concepts of maximum response and sensitivity determine the magnitude of the effect at a particular concentration (see E max and C 50 , Chapter 2

But the difference between something that works and something that doesnt often has very little to do with the name on the vial

The solution is clear

For research consistency, purified laboratory-grade water is commonly used when reconstituting peptide compounds