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Welch-Reardon, K

The bistability of thalamic and cortical neurons during NREM sleep impairs cortical information transmission and corticocortical effective connectivity NREM sleep is further divided into four Stages from the lightest Stage 1 to the deepest Stage 4

Similarly, intraperitoneal administration of 0.25 mg/kg and 0.50 mg/kg and oral administration of 2.0 mg/kg of Dihexa significantly improved performance to levels comparable with vehicle controls

These mice were shown to have higher mortality rates and tissue damage

Is this where were at right now

To identify miRNAs accumulating in Zswim8 -knockout lines compared with control lines, reads associated with all isoforms of a given miRNA were summed, filtered on the basis of a read cutoff of greater than five reads per library for at least two of the knockout lines and 30 reads across all six lines (three knockouts and three controls) and normalized for sequencing depth using the estimateSizeFactors function of DESeq2 (v.1.38.3) 87