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Vitamin A (retinol) is important for the function of the immune system due to its anti-inflammatory effects

Leong, Huiyu Lin, MengTzu Weng, Wan Chee Ong, Vineet Ahuja, Satimai Aniwan, Ryota Hokari, Wei Jie Jonathan Lee, Alex HwongRue Journal of Gastroenterology and Hepatology.2026

Nature 635, 453461

10.1080/17435889.2025.2457315 176 WangH.ZhangH.SunL.GuoW

In addition, the beneficial bacterium up-regulated the expression of several defense genes encoding PR-10a, the antioxidative monodehydroascorbate reductase enzyme and two GSTs (Maketon et al., 2012)

Cell Death Differ 25(3):486541 Gao J et al (2018) Downregulation of GSDMD attenuates tumor proliferation via the intrinsic mitochondrial apoptotic pathway and inhibition of EGFR/Akt signaling and predicts a good prognosis in non-small cell lung cancer