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Use of thiols in the treatment of COVID-19: current Evidence

Free Radical Biol Med 4(4):219223 Candeias LP, Steenken S (2000) Reaction of HO* with guanine derivatives in aqueous solution: formation of two different redox-active OH-adduct radicals and their unimolecular transformation reactions

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A striking example is curcumins synergy with antibiotics against resistant organisms: curcumin greatly improved the efficacy of polymyxin and vancomycin against both Gram-negative and Gram-positive pathogens by increasing cell membrane permeability and blocking drug efflux ( Candida (fungal) cells as wellcurcumin interacts with membrane ergosterol, akin to polyene antifungals, leading to membrane destabilization

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Conclusion: In Child Pugh A patients, prophylactic EGD prior to treatment did not affect bleeding outcomes