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The peptide's muscle-protective properties extend beyond genetic muscle diseases, with potential applications in preventing exercise-induced muscle damage, accelerating recovery from injury, and maintaining muscle mass during periods of disuse or immobilization

Platelet MAPK signaling molecules mainly include ERKs (extracellular-signal-regulated kinases), JNKs (Jun amino-terminal kinases), and p38/SAPKs (stress-activated protein kinases)

Third-generation EGFR-TKI osimertinib, developed to overcome T790M mutation-driven resistance, is now a first-line option for advanced EGFR-mutant NSCLC [3, 4]

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Common reactions at the injection site include irritation, itching, and swelling

7.1.4 Response to treatment should be assessed after exclusion of sub-optimal dosing, non-adherence, alternative etiologies, co-morbidities, and autoimmune sclerosing cholangitis/overlap syndrome (LOE 5, Strong recommendation)