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AFSCs exhibit expression of OCT4 and additional pluripotency markers, while preserving a rapid self-renewal capacity, maintaining a normal karyotype in long-term culture, and demonstrating low immunogenicity, which enables them to evade immune rejection

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By doing so, ozone therapy is administered in various acute and chronic musculoskeletal disorders such as fractures [4,5,6], osteoarthritis (OA) [7,8,9,10], low back ache [11, 12], osteomyelitis [13,14,15,16], and chronic pain syndromes [17,18,19]