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In contrast to GSSG, which had no impact on the roGFP2 oxidation rate in WT, cystine massively reduced the time until full oxidation was reached (Fig

Andrews NP et al

This imbalance results in a reduction of antioxidants like glutathione, which can lead to the improper formation of disulfide bonds

This process is significant in numerous biological and pathological contexts and is implicated in the onset and progression of a wide array of human diseases