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Not taking B12 supplements or regularly eating B12 fortified foods may explain the higher stroke

Because AOD-9604 does not suppress appetite mechanisms in the first place, there is no adaptation of hunger-regulating neurons and no compensatory hunger amplification when the peptide is stopped

Most relevant peptides: Thymosin alpha-1 for restoring T cell regulation and reducing autoantibody production KPV for systemic NF-kB inhibition and cytokine reduction An important lupus-specific peptide in clinical development is P140/Lupuzor, a 21-amino-acid phosphopeptide that has completed Phase IIb clinical trials and entered Phase III trials for SLE

It would make an interesting survey to see how many of each type did different things - like supplement with folic acid/folate

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So are GLP 1 medications like Ozempic