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Blood plasma samples were collected in heparin (100 U ml 1 ) pretreated tube and centrifuged at 1500 g for 10 min

High dose androgen suppresses natural killer cytotoxicity of castration-resistant prostate cancer cells via altering AR/circFKBP5/miRNA-513a-5p/PD-L1 signals

Zhao M, Zhang Y, Li J, Li X, Cheng N, Wang Q, et al

I.LiX.et al (2018)

In vitro studies have found that in IDH1 mutant glioma stem cells (TS603), the expression of genes related to ROS clearance is overall upregulated, and the gene that regulates glutathione synthesis, SLC7A11, is most upregulated

Track dosing in a clear plan: starting dose, escalation steps, monitoring frequency, and stop rules for adverse events