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Moreover, male gonads cultured in the presence of IGF-I increased testosterone production during testicular development [130]

It is a central enzyme of cellular antioxidant defense

However, such hyperactivation of brain circuits is associated with poorer, not better cognitive performance in individuals with MCI but also in non-cognitively impaired ApoE4 carriers, in young Down syndrome individuals 164 , in aged individuals 165 and in aged rats 166

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Springer, Cham, pp 191217 Zhou Q, Yang N, Li Y et al (2020) Total concentrations and sources of heavy metal pollution in global river and lake water bodies from 1972 to 2017

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