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However, even when isolated, surgery may be indicated to: relieve direct pressure on the brain, clean contaminated wounds, repair and close a lacerated dura (common with depressed fractures), prevent infection and persistent CSF leakage, and for cosmetic reasons , particularly when the fracture involves the forehead

Pereira, J

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This review provides a comprehensive overview of the classification and molecular mechanisms of antifungal drugs, discusses the current challenges in antifungal therapy, and explores potential strategies for future drug development, aiming to inform and advance antifungal research and treatment

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