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Similar to that in the Gpx4 flox/flox Vav-Cre mice, the HSPC phenotype was not impaired in the Gpx4 flox/flox Mx-Cre mice treated with pIpC (Supplementary Fig

Buckingham, E

doi:10.1111/j.1472-8206.2011.01015.x

43 Notably, single MCT4 inhibition can reverse lactate-driven immunosuppression and increase the efficacy of immune checkpoint blockade (ICB) therapy

Amyotrophic Lateral Sclerosis (ALS) is a devastating multisystem neurodegenerative disease characterized by the degeneration of both upper (cortical) and lower (brainstem and spinal) motor neurons, leading to progressive voluntary muscle weakness and paralysis

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