chac1 glutathione (GSH) depletion by results in a more oxidizing Human CHAC1 Protein Degrades Glutathione,

Human CHAC1 Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF CRE Regulatory Element ScienceDirect Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC Nature Communications Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv Glutathione Peroxidase 8 Suppression by Histone Deacetylase Inhibitors Enhances Endoplasmic Reticulum Stress and Cell Death by Oxidative Stress in Hepatocellular Carcinoma Cells BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress L 2 Hydroxyglutarate sensitizes ferroptosis through ATF3 CHAC1 mediated glutathione degradation in hepatocellular carcinoma Cell Death & Disease

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