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In Drosophila , enhancing BNIP3-mediated mitophagy in the nervous system improves mitochondrial homeostasis, thereby extending lifespan, and improving muscle and gut homeostasis

Introduction In clinics, many pathogens are hard to eradicate even in the absence of genetically detectable anti-microbial resistance (AMR) mechanisms, and despite proven antibiotic susceptibilities in antimicrobial sensitivity testing (AST) ( Box 1 )

In vivo efficacy studies In the pilot study, HCT116 cells (1 10 6 ) in exponential phase were injected subcutaneouslyinto the left flank of 8- to 10-week-old female nude mice (2530 g

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