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Gunn CM, Pankowska M, Harris M, Helsing E, Battaglia TA, Bagley SM

In 2009, a study found that PINK1 regulates calcium outflow from mitochondria through the mitochondrial Na + /Ca 2+ exchanger

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A 2 (7), 21102118

Physiological, beneficial functions have been described in oncogene-expressing cells, where senescence acts as a tumor-suppressive mechanism, in wound healing (Demaria et al., 2014), and during embryonic development, contributing to proper tissue formation (Muoz-Espn et al., 2013

120 The active metabolite salicylate has been proposed to contribute to aspirins anticancer effects, further supporting the need for continued research into its mechanisms