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Clinics like Aura Regenerative Center utilize COFEPRIS-approved technologies and full traceability documentation

Additionally, developing optimal formulations to overcome potential bioavailability challenges, conducting proof-of-concept investigations in human-derived liver cell models, and performing well-designed early-phase clinical trials in patients with MASLD and T2DM will be crucial to validate its therapeutic potential, evaluate its effects on liver histology and metabolic parameters, and determine its integration with existing standard-of-care therapies

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Incorporating studies with negative or null results will help mitigate publication bias and contribute to a more accurate, evidence-based understanding of the role of natural products in AD

Human research remains in its early stages

Pine bark phenolic extracts, current uses, and potential food applications: A review